Overview Introduction Trajenta Duo 2.5mg/500mg Tablet is a combination of two medicines that control high blood sugar levels in people with type 2 diabetes mellitus. This helps prevent serious complications of diabetes such as kidney damage and blindness and may reduce your chance of having a heart attack or stroke. Trajenta Duo 2.5mg/500mg Tablet can be prescribed alone or together with other diabetes medications. All diabetes medicines work best when used along with a healthy diet and regular exercise. The dose you are given will depend on your condition, blood sugar levels and what other medicines you are taking. Taking this medicine with meals helps to reduce the chances of developing an upset stomach. You should take it regularly, at the same time each day, to get the most benefit. You should not stop this medicine unless your doctor recommends it. It is controlling your blood sugar levels and helping to prevent serious complications in the future. Your lifestyle plays a big part in controlling diabetes. Therefore, it is important to stay on the diet and exercise program recommended by your doctor while taking this medicine. The most common side effects of taking this medicine include diarrhea, nausea, vomiting, upset stomach, headache, blocked nose (nasal congestion) and sore throat. Low blood sugar level (hypoglycemia) is a possible side effect if you are also taking other diabetes medicines like insulin, glimepiride, or sulphonylurea. So you need to know how to recognize and deal with it. This medicine is not suitable for everyone. Before taking it, you should let your doctor know if you have ever had kidney, liver or heart disease, problems with your pancreas, or if you drink a lot of alcohol. Pregnant or breastfeeding women should also consult their doctor before taking this medicine. Some other medicines MAY affect the working of this medicine, so tell your doctor about all the medicines you are taking to make sure you are safe. You should try to avoid drinking alcohol as it lowers blood sugar. Your doctor will check your kidney function and blood sugar levels before and during treatment. Uses of Trajenta Duo Tablet Type 2 diabetes mellitus Benefits of Trajenta Duo Tablet In Type 2 diabetes mellitus Trajenta Duo 2.5mg/500mg Tablet has two active substances in it i.e. metformin and linagliptin. Metformin belongs to a class of medicines called biguanides. Linagliptin belongs to a group called DPP-4 inhibitors. They work together in different ways to lower your blood glucose levels. Lowering blood glucose levels is an essential part of managing diabetes. If you can control your blood glucose level, your risk of getting any of the serious complications of diabetes such as kidney damage, eye damage, nerve problems, and loss of limbs is also lowered. Additionally, proper control of diabetes can also reduce the risk of heart disease and stroke. Taking this medicine regularly along with a proper program of diet and exercise will help you live a normal, healthy life. You should keep using this medicine for as long as it is prescribed because it is protecting your future health. Side effects of Trajenta Duo Tablet Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Trajenta Duo Diarrhea Nausea Vomiting Upset stomach Headache Nasal congestion (stuffy nose) Sore throat Respiratory tract infection Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea How to cope with side effects? The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist. Coping with Diarrhea Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments. Coping with Nausea You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve. Coping with Vomiting You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve. Coping with Upset stomach Try taking your medicine with a meal or snack, or shortly after eating. It might help to eat smaller and more frequent meals, and to eat and drink slowly. Avoid foods which can irritate your stomach such as carbonated soft drinks, caffeine, fatty and spicy foods, mints and citrus fruits. Quit smoking and alcohol because they increase the symptoms. Do not eat for 3 or 4 hours before going to bed. Try raising the head of your bed at night or use extra pillows. Ask your doctor or pharmacist about medicines that may help, such as antacids, if your condition does not improve. Coping with Headache Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller. Coping with Nasal congestion (stuffy nose) Try saline spray or nose drops. Taking steam inhalation or placing a warm wet towel on your face can also help. Use a humidifier if the air in your house is too dry. Using an extra pillow at night to lift up your head can also improve your breathing. If your condition does not improve, you should talk to your doctor. The doctor may be able to prescribe you certain over-the-counter medicines that can help improve your condition. Coping with Sore throat Try gargling with warm salt water as it can help soothe a scratchy throat and relieve the discomfort. Stay hydrated by drinking plenty of water. Consider lozenges or hard candy. Avoid caffeine and alcohol, as they can dry out your throat and aggravate the symptoms. Also, avoid smoking or smoky places. Warm tea that is sweetened with honey can also soothe your irritated throat. Get plenty of rest and consider using a humidifier if the air in your home is dry. If it does not get better or get worse, talk to your doctor for advice. show more show less How to use Trajenta Duo Tablet Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Trajenta Duo 2.5mg/500mg Tablet is to be taken with food. How Trajenta Duo Tablet works Trajenta Duo 2.5mg/500mg Tablet is a combination of two antidiabetic medicines: Metformin and Linagliptin. Metformin is an antidiabetic medication (biguanide). It works by lowering the glucose production in the liver, delaying glucose absorption from the intestines and increasing the body's sensitivity to insulin. Linagliptin is a DPP-4 inhibitor which works by increasing the release of insulin from the pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Together, they provide better control of blood sugar. Safety Advice Alcohol UNSAFE It is unsafe to consume alcohol with Trajenta Duo 2.5mg/500mg Tablet. Pregnancy SAFE IF PRESCRIBED Trajenta Duo 2.5mg/500mg Tablet is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies. Breastfeeding SAFE IF PRESCRIBED Trajenta Duo 2.5mg/500mg Tablet is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby. Driving CAUTION Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur. Kidney CAUTION Trajenta Duo 2.5mg/500mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Trajenta Duo 2.5mg/500mg Tablet may be needed. Please consult your doctor. Use of Trajenta Duo 2.5mg/500mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine. Liver CAUTION Trajenta Duo 2.5mg/500mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Trajenta Duo 2.5mg/500mg Tablet may be needed. Please consult your doctor. Trajenta Duo 2.5mg/500mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease. What if you forget to take Trajenta Duo Tablet? If you miss a dose of Trajenta Duo 2.5mg/500mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
